Smart Formula 3D accelerates drug elucitation automatic formulae determination with ESI-TOF mass spectrometry

This July, the USP is adopting a modified version of the ICH Quality-3C methodology. This revision provides a risk-based approach to residual solvent analysis that considers exposure to a solvent residue in the drug product. Herein, we discuss the main advantages/disadvantages of using headspace vs direct liquid injection techniques to meet the <467> guidelines.

The alternative fuel is increasing in popularity owing to various technical and economic factors, especially the upsurge in petroleum prices and the implementation of financial incentives for its use. According to the National Biodiesel Board, the sales volume of the alternative fuel in the US has risen from 50000 gallons in 1999 to 75 million gallons in 2005.1

The four primary driving forces behind biofuels are the world's increasing thirst for petroleum (80 Mbarrels/day), the diminishing supply of fossil fuels, global warming and the intention to reduce the dependence on fuel imports.

Phthalates are added to plastics to increase flexibility. Recently, concerns have been raised over the effect of phthalate exposure from plastic materials on human health.